Job Description: A Senior Principal Scientist position is available within the Purification Process Development (PPD) group in Bioprocess R&D. The successful applicant will be responsible for developing innovative, robust, efficient, and scalable purification processes and technologies required for the advancement of a diverse and extensive portfolio of large molecules including proteins and vaccines. They will be expected to provide strong technical, strategic and organizational leadership so as to ensure efficient and timely execution of PPD deliverables. The position will focus on process design, unit operation scale-up and scale-down and apply rigorous scientific and engineering principles and approaches to all aspects of purification process development. Job Responsibilities: Experience developing commercially relevant process for products derived from mammalian and microbial processes. Demonstrated experience with managing multiple development projects in parallel, including key participation on multi-disciplinary project teams. Experience in supporting the scale-up and technology transfer to pilot / commercial scale. Good knowledge of GLP/GMP and Biotechnology CMC regulatory requirements. Extensive knowledge of drug development (with a particular strength in the area of purification process technologies). Demonstrated supervision / leadership of high caliber engineers and scientists; ability to mentor junior staff and peers Familiarity with process development utilizing quality risk management and quality by design concepts. Experience with all aspects of membrane filtration, viral clearance and filtration. Excellent oral and written communication skills. Experience with chromatographic and membrane based separations. Job Requirements: Demonstrated leadership success in both project and people management. This position requires highly motivated individuals with the ability to work closely with other members of the laboratory and the department in a matrix team environment to also drive novel innovative technology strategies. Over 8-15 years relevant work experience in Chemical/Biochemical Engineering, Biochemistry, or equivalent, including process development, process scale-up, technology transfer, and support for process validation and commercial production, within the Biopharmaceutical industry. The candidate should have demonstrated technical expertise in developing chromatographic and membrane based separation processes including familiarity with mRNA processesing. Experience contributing to regulatory submissions including IND, BLA, and MAA is required. Demonstrated ability to drive for results and lead innovation and change. Ph.D. degree in Chemical/Biochemical Engineering, Biochemistry, or equivalent with 8+ years of experience or Masters degree with 15+ years of experience The successful candidate will possess strong oral and written communication skills. Strong analytical and computer skills are required. Preferred Qualifications Collaborative, team oriented leadership and management style essential. Applicants should be bright, organized, self-motivated, and capable of working independently, and in a collaborative environment. Job Details: Company: Pfizer Vacancy Type: Full Time Job Location: St. Louis, MO, US Application Deadline: N/A Apply Here careers-trivia.com
Careers Trivia – Latest Jobs 2025